Grant number: 106403 | Funding period: 2021 - 2027
Active
Q Cheng, C Watts, R Al Adawiyah, R Guy, JJ Ong, CS Bradshaw, V Wiseman
2026-12-01
As macrolide-resistant Mycoplasma genitalium (MG) becomes more prevalent, resistance-guided therapy (RGT) for MG has been recommen..
SJ Low, MT O’Neill, JA Fernando, WJ Kerry, J Prestedge, N Wild, S Chahal, GL Pollock, G Papadakis, M Krysiak, E Williams, F Azzato, T Tran, C Fairley, C Bradshaw, MY Chen, CK Lim, DA Williamson, S Pasricha
2026-04-01
Background Timely, point-of-care diagnosis of sexually transmitted infections (STIs) is crucial for enabling prompt treatment and ..
A Wong, N Lima, TL Applegate, R Guy, WM Huston, JS Hocking, D Boettiger
2026-01-15
Background. Modern assays for the detection of Chlamydia trachomatis (CT) rely on nucleic acid amplification testing (NAAT) of DNA..
S Chandra, A Broom, D Ridge, B Haire, C Bradshaw, J Broom, M Peterie, L Lafferty, T Applegate, R Guy
2026-01-01
Sexual health has always been a social matter. While the science of disease transmission remains a focus for public health stakeho..
S Chandra, A Broom, D Ridge, B Haire, M Peterie, C Bradshaw, J Broom, L Lafferty, C Treloar, T Applegate, R Guy
Often, research takes place once a health issue is already at ‘crisis’ point. However, health professionals and populations can ha..
JL Huaman, CS Bradshaw, TP Chua, EL Plummer, JA Danielewski, LA Vodstrcil, SM Garland, GL Murray
Mycoplasma genitalium is a fastidious human pathogen with increasing antimicrobial resistance, yet its genomic landscape remains p..
SJ Low, M O’Neill, WJ Kerry, N Wild, M Krysiak, Y Nong, F Azzato, E Hor, L Williams, G Taiaroa, E Steinig, S Pasricha, DA Williamson
2025-12-01
Critical to the success of CRISPR-based diagnostic assays is the selection of a diagnostic target highly specific to the organism ..
TP Chua, JL Huaman, J Danielewski, CS Bradshaw, DA Machalek, MJ McDonald, SM Garland, GL Murray
2025-11-01
Background: Current knowledge of Mycoplasma genitalium fluoroquinolone resistance is based on sequence analyses of clinical sample..
TP Chua, JA Danielewski, JL Huaman, EL Plummer, CS Bradshaw, LA Vodstrcil, DA Machalek, SM Garland, GL Murray
2025-10-01
Mycoplasma genitalium is challenging to work with and new methods are needed to study this bacterium directly in clinical samples...
S Chandra, A Broom, D Ridge, K Kenny, M Peterie, J Broom, B Haire, L Lafferty, C Treloar, S Raymond, C Bradshaw, T Applegate, R Guy
2025-08-01
Few studies have explored community experiences of our increasingly resistant bacterial landscape, and, in the sphere of sexually ..
K Do, M Unemo, C Kenyon, JS Hocking, FYS Kong
Objectives Doxycycline post-exposure prophylaxis (doxyPEP) can reduce incident sexually transmitted infections including gonorrhoe..
TP Chua, J Danielewski, CS Bradshaw, DA Machalek, SM Garland, JL Huaman, JS Jensen, GL Murray
2025-07-01
Background Mycoplasma genitalium is a sexually transmitted bacterium of increasing concern due to issues around antimicrobial resi..
TP Chua, LA Vodstrcil, GL Murray, EL Plummer, JS Jensen, M Unemo, EPF Chow, N Low, DM Whiley, EL Sweeney, JS Hocking, JA Danielewski, SM Garland, CK Fairley, L Zhang, CS Bradshaw, DA Machalek
Background: Over the past 5 years, since publication of the initial review, studies have provided additional data on macrolide and..
P Chen, T Zhang, C Li, P Praveen, K Parisi, C Beh, S Ding, JD Wade, Y Hong, S Li, JN Nkoh, A Hung, W Li, C Shang
2025-01-15
Aggregation of antimicrobial peptides (AMPs) enhances their efficacy by destabilising the bacterial cell wall, membrane, and cytos..
L Giacani, CS Bradshaw, CA Muzny, KJ Graves, S Pasricha, SJ Jordan, LT Allan-Blitz
2025-01-01
Purpose of Review: Antimicrobial resistance in sexually transmitted infections (STIs) has become an urgent global public health th..
SA Hamza, R Paolini, C Moore, M Unemo, M McCullough, JS Hocking, C Kahler, A Celentano, FYS Kong
Objectives The global rise in Neisseria gonorrhoeae (NG) infections, particularly oropharyngeal cases, drives treatment failures f..
JL Huaman, CS Bradshaw, TP Chua, EL Plummer, JA Danielewski, LA Vodstrcil, JS Jensen, SM Garland, N Wild, GL Murray
Introduction. Mycoplasma genitalium, a small and slow-growing bacterium, has gained notoriety due to rapidly increasing rates of a..
ML Taouk, G Taiaroa, S Duchene, SJ Low, CK Higgs, DYJ Lee, S Pasricha, N Higgins, DJ Ingle, BP Howden, MY Chen, CK Fairley, EPF Chow, DA Williamson
2024-12-01
N. gonorrhoeae, which causes the sexually transmissible infection gonorrhoea, remains a significant public health threat globally,..
Y Zhang, LA Vodstrcil, K Htaik, EL Plummer, V De Petra, MG Sen, DA Williamson, M Owlad, G Murray, EP Chow, CK Fairley, CS Bradshaw, JJ Ong
2024-07-01
Background: Current clinical care for common bacterial STIs (Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG) and Mycoplasma..
SFE Bell, EL Sweeney, FYS Kong, DM Whiley, CS Bradshaw, JA Tickner
2024-04-15
LA Vodstrcil, K Htaik, EL Plummer, V De Petra, MG Sen, DA Williamson, JJ Ong, J Wu, M Owlad, G Murray, EPF Chow, CK Fairley, CS Bradshaw
2024-03-01
Background: Empiric treatment of sexually transmitted infections can cause unnecessary antibiotic use. We determined if near-to-pa..
R Sacks-Davis, DK van Santen, A Boyd, J Young, A Stewart, JS Doyle, A Rauch, C Mugglin, M Klein, M van der Valk, C Smit, I Jarrin, J Berenguer, K Lacombe, MB Requena, L Wittkop, O Leleux, F Bonnet, D Salmon, GV Matthews
2024-02-01
Background: Reinfection after successful treatment with direct-acting antivirals is hypothesised to undermine efforts to eliminate..
Nicole G Ertl, Taylah K Anderson, Carolyn J Pardo, Toby Maidment, Gerald L Murray, Catriona S Bradshaw, David M Whiley, Emma L Sweeney
EPF Chow, CK Fairley, FYS Kong
Purpose of reviewThe rise in antimicrobial resistance in several STI pathogens such as Neisseria gonorrhoeae has become a public h..
Janath A Fernando, Marcelina Krysiak, Jacqueline Prestedge, Francesca Azzato, Deborah A Williamson, Shivani Pasricha
2024-01-01
OBJECTIVES: To ensure accurate diagnosis of infectious diseases, preanalytical factors should be considered when assessing specime..
FYS Kong, C Kenyon, M Unemo
2023-07-01
Rates of sexually transmitted infections (STIs) continue to rise across the world and interventions are essential to reduce their ..
CR Peh, J Danielewski, TP Chua, K Bodiyabadu, DA Machalek, SM Garland, CS Bradshaw, GL Murray
2023-06-01
Mycoplasma genitalium is a sexually transmitted infection with increasing concerns around antimicrobial resistance. Droplet digita..
LA Vodstrcil, EL Plummer, M Doyle, GL Murray, K Bodiyabadu, JS Jensen, D Whiley, E Sweeney, DA Williamson, EPF Chow, CK Fairley, CS Bradshaw
2022-09-01
Background: Mycoplasma genitalium (MG) infection is challenging to cure because of rising antimicrobial resistance and limited tre..
EL Sweeney, CS Bradshaw, GL Murray, DM Whiley
Mycoplasma genitalium is an emerging global health threat, due to an alarming rise in antimicrobial resistance. Although individua..
JA Tickner, CS Bradshaw, GL Murray, DM Whiley, EL Sweeney
2022-06-01
Background: Mycoplasma genitalium infection is a sexually transmitted infection that has rapidly become resistant to mainstay trea..
EL Sweeney, DM Whiley, GL Murray, CS Bradshaw
2022-05-27
Mycoplasma genitalium is an emerging sexually transmitted bacterium that is gaining attention because of the impact escalating ant..
TP Chua, J Danielewski, K Bodiyabadu, CS Bradshaw, DA Machalek, SM Garland, EL Plummer, LA Vodstrcil, GL Murray
2022-05-01
Doxycycline targets the 16S rRNA and is widely used for the treatment of sexually transmitted infections. While it is not highly e..
GL Murray, K Bodiyabadu, LA Vodstrcil, DA Machalek, J Danielewski, EL Plummer, SM Garland, DM Whiley, EL Sweeney, CS Bradshaw
Prevalence, trends, and treatment outcome estimates were generated for parC variants in macrolide-resistant Mycoplasma genitalium...